Showing posts with label Basic medical sceience. Show all posts
Showing posts with label Basic medical sceience. Show all posts

Emerging Pathologies in Cardiology: Proceedings of the Mediterranean Cardiology Meeting 2005 free medical book download

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Product Details
Book Publisher: Springer (31 December, 1899)
ISBN: 8847003113
Book author: M.M. Gulizia

Book Description:
The book aims to give the most up-to-date information about the epidemiology, the pathophysiology, the diagnosis and the new treatments of the Emerging Pathologies in Cardiology. It presents the state of the art on Acute Coronary Syndromes, Sudden Cardiac Death, Heart Failure, Atrial Fibrillation, Syncope and Prevention of Global Cardiovascular Risk which are some of the emerging pathologies urging investigators to develop many and more sophisticated pharmacological, electrical or mechanical therapies. The volume chapters are written by world-renowned leading experts in these fields, and present a detailed analysis of the most recent developments in the treatment of the above mentioned cardiac pathologies.

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Rotavirus: Methods & Protocols (Methods in Molecular Medicine) free medical book download



Product Details
»ISBN: 0896037363
»Book author: James Gray, Ulrich Desselberger

Book Description:
Addenbrooke’s Hospital, Cambridge, UK. Collection of established methods for studying the structure, molecular biology, pathogenesis, epidemiology, and prevention in animal models of infection with rotaviruses, a cause of infant morbidity and mortality. Expanded-outline format. DNLM: Rotavirus Laboratory Manuals.

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Epidemiology of Pediatric and Adolescent Diabetes free medical book download


* Publisher: Informa HealthCare
* Number Of Pages: 376
* Publication Date: 2008-02-08
* ISBN-10 / ASIN: 1420047973
* ISBN-13 / EAN: 9781420047974
* Binding: Hardcover

Product Description:
The epidemiology of diabetes in children and adolescents is changing, which carries profound implications for how clinicians screen, assess, and manage the world-wide epidemic of this chronic disease. Over the past few years, as the incidence of childhood obesity has dramatically increased, so has the emergence of Type 2 diabetes in young people, as well as the incidence of diabetic diagnoses anomalies that do not conform to the standard type1 or type 2 classification models.

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Neurodegeneration and Neuroprotection in Parkinson's Disease (Neuroscience Perspectives) free book download



* Publisher: Academic Press
* Number Of Pages: 224
* Publication Date: 1996-04-26
* ISBN-10 / ASIN: 0125254458
* ISBN-13 / EAN: 9780125254458
* Binding: Hardcover

Product Description:
Neuroscience Perspectives provides multidisciplinary reviews of topics in one of the most divers and rapidly advancing fields in the life sciences. Whether you are a new recruit to neuroscience, or an established expert, look to this series for 'one-stop' sources of the historical, physiological, pharmacological, biochemical, molecular biological, and therapeutic aspects of chosen research areas.

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Bayesian Brain: Probabilistic Approaches to Neural Coding free book download



* Publisher: The MIT Press
* Number Of Pages: 340
* Publication Date: 2007-01-01
* ISBN-10 / ASIN: 026204238X
* ISBN-13 / EAN: 9780262042383
* Binding: Hardcover

Product Description:
A Bayesian approach can contribute to an understanding of the brain on multiple levels, by giving normative predictions about how an ideal sensory system should combine prior knowledge and observation, by providing mechanistic interpretation of the dynamic functioning of the brain circuit, and by suggesting optimal ways of deciphering experimental data.

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Nitric Oxide in the Nervous System (Neuroscience Perspectives) free book download



Publisher: Academic Press
Number Of Pages: 317
Publication Date: 1995-05-01
ISBN-10 / ASIN: 0127219854
ISBN-13 / EAN: 9780127219851
Binding: Hardcover

Product Description:
The gas nitric oxide (NO) has burst upon neuroscience only recently, and yet it has permeated into almost every avenue of current research. The unique properties of this novel messenger have revolutionized our way ofthinking about neurotransmission. These special properties have also lead neuroscientists to invoke NO to explain many previously unexplained phenomena in neurobiology.

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Case Files: Neuroscience (Case Files) free book download



* Publisher: McGraw-Hill Medical
* Number Of Pages: 408
* Publication Date: 2008-08-15
* ISBN-10 / ASIN: 0071489215
* ISBN-13 / EAN: 9780071489218
* Binding: Paperback

Product Description:
REAL LIFE CLINICAL CASES FOR THE BASIC SCIENCES AND USMLE STEP 1
You need exposure to clinical cases to pass course exams and ace the USMLE Step 1. Case Files: Neuroscience presents 50 real-life clinical cases illustrating essential concepts in microbiology. Each case includes and easy-to-understand discussion correlated to key basic science concepts, definitions of key terms, neuroscience pearls, and USMLE-style review questions. This interactive system helps you learn instead of memorize.

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Therapeutic Strategies in Dementia free book download



* Publisher: Clinical Publishing
* Number Of Pages: 352
* Publication Date: 2006-11-30
* ISBN-10 / ASIN: 190439258X
* ISBN-13 / EAN: 9781904392583
* Binding: Hardcover

Product Description:
Widely acknowledged as one of the most challenging aspects of dealing with an aging population, the increasing prevalence of cognitive decline in the elderly presents the clinician with a variety of complex therapeutic problems. Alzheimer's disease and other dementias vary in their onset and progression, as do patients in their responsiveness to treatment - social management is as important as the choice of therapeutic agent, and implementing effective and sympathetic treatment requires care and sensitivity as well as a sound knowledge of currently available options.

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Neurotransmitter Receptors free book download



* Publisher: Elsevier Science Pub Co
* Number Of Pages: 386
* Publication Date: 1994-03-01
* ISBN-10 / ASIN: 0444899030
* ISBN-13 / EAN: 9780444899033

Product Description:
Hardbound. This comprehensive compilation provides a wealth of information on receptor sequences produced by recombinant DNA techniques used in combination with classical biochemistry. To minimize redundancies in this wealth of information, only a few receptors (some of which are typical for a whole group of similar receptors, others which are presently of special interest) are dealt with in a full-size chapter. Others are represented in the TIPS Receptor Nomenclature Supplement which is included as a special feature in this book, making this volume more useful as a receptor handbook.

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Sabiston & Spencer Surgery of the Chest: 2-Volume Set 7 ed free book download

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2480 pages
Trim size 8 1/2 X 10 7/8 in
Copyright 2005
$314.00, Hardcover, Reference

Saunders Title
ISBN: 0721600921
ISBN-13: 9780721600925

Description
A brand-new team of editors and a multitude of new international contributors have completely revamped and updated Sabiston and Spencer's classic reference work. The result is today's only comprehensive, up-to-date collection of all essential clinical knowledge in cardiac and thoracic surgery. The contents have been reorganized into three major sections—***** Cardiac Surgery, Pediatric Cardiac Surgery, and Thoracic Surgery. And, more than 50 new chapters have been added to reflect important changes within this rapidly evolving field, including both surgical and medical therapeutic approaches. More than 1,500 illustrations, nearly all of them new to this edition, help to clarify key concepts.

With 200 additional contributors

Reviews
"This is undoubtedly the most comprehensive textbook on surgery of the chest...[It] must be considered an essential reference source not only for all thoracic surgeons, but also for all physicians, residents, and students concerned with diseases of the chest." —Annals of Surgery

Key Features

Features a new organization into three major sections—***** Cardiac Surgery, Pediatric Cardiac Surgery, and Thoracic Surgery—that makes information
Covers hot new topics in thoracic surgery including minimal invasive treatment of lung cancer • multimodal therapy for esophageal cancer • innovative therapies and technology in thoracic surgery • and endoscopic treatment of thoracic disease.
Explores new developments in ***** cardiac surgery, such as catheter-based treatment of coronary disease • advances in cardiac pacing and pacemakers • valve replacement therapy • Left Ventricular Assist Devices • and bypass grafting for coronary
Addresses important new areas of pediatric cardiac surgery, such as cardiac catheterization and catheter-based interventions • transposition of the great arteries • congenital anomalies of the mitral valve • surgery for arrhythmias • and pacemakers in children.
Offers oversight from a brand-new editorial team, and contributions from a multitude of new authors from around the world—to present fresh perspectives on every aspect of the field.

Author Information
By Frank Sellke, MD, Johnson & Johnson Professor of Surgery, Harvard Medical School, Chief, Division of Cardiothoracic Surgery, Beth Israel Deaconess Medical Center, Boson, MA; Scott Swanson, MD, Eugene F. Friedman Professor of Oncology; Chief Division of Thoracic Surgery, Mt. Sinai School of Medicine, New York, NY.; and Pedro J. del Nido, MD, Professor of Surgery, Harvard Medical School, Senior Associate in Cardiovascular Surgery, Children's Hospital, Boston, MA.

Description
A brand-new team of editors and a multitude of new international contributors have completely revamped and updated Sabiston and Spencer's classic reference work. The result is today's only comprehensive, up-to-date collection of all essential clinical knowledge in cardiac and thoracic surgery. The contents have been reorganized into three major sections?***** Cardiac Surgery, Pediatric Cardiac Surgery, and Thoracic Surgery. And, more than 50 new chapters have been added to reflect important changes within this rapidly evolving field, including both surgical and medical therapeutic approaches. More than 1,500 illustrations, nearly all of them new to this edition, help to clarify key concepts.

Audience
Cardiac Surgeons and General Thoracic Surgeons, General Surgeons, Residents and Fellows, and Health Science Libraries

Contents


SECTION I Thoracic

EVALUATION AND CARE
1 Anatomy of the Thorax
2 Imaging the Thorax
3 Preoperative Assessment of the Thoracic Surgery Patient
4 Perioperative Care of the Thoracic Surgical Patient
ENDOSCOPY
5 Endoscopic Diagnosis of Thoracic Disease
6 Endoscopic Therapies for the Airway and the Esophagus
TRAUMA
7 Thoracic Trauma
TRACHEA
8 Tracheal Lesions
BENIGN LUNG DISEASE
9 Congenital Lung Disease
10 Benign Lesions of the Lung
11 Interstitial Lung Diseases
12 Infectious Lung Diseases
13 Surgery for Emphysema
14 Lung Transplantation
LUNG CANCER
15 Screening for Lung Cancer
16 Lung Cancer Work-Up and Staging
17 Lung Cancer – Surgical Treatment
18 Lung Cancer – Minimally Invasive Treatment
19 Lung Cancer – Multimodal Therapy
20 Lung Cancer – Surgical Strategies for Tumors Invading Chest Wall
21 Anterior Approach to Pancoast Tumors
OTHER LUNG MALIGNANCY
22 Other Primary Tumors of the Lung
23 Secondary Lung Tumors
CHEST WALL
24 Congenital Chest Wall Deformities
25 Chest Wall Tumors
26 Chest Wall Reconstruction
27 Thoracic Outlet Syndrome: Dorsal Sympathectomy
PLEURA
28 Benign Pleural Disease (including chylothorax, empyema, fibrothorax, pneumothorax)
29 Malignant Pleural and Pericardial Effusions
30 Pleural Tumors
DIAPHRAGM
31 Diaphragmatic Disorders & Therapy
32 Congenital Diaphragmatic Hernias
ESOPHAGUS – BENIGN DISEASE
33 Esophageal Physiology and Function
34 Surgery for Congenital Lesions of the Esophagus
35 Treatment of Benign Esophageal Disease
ESOPHAGUS - CANCER
36 Esophageal Cancer – Work-Up and Staging
37 Esophageal Resection and Replacement
38 Esophageal Cancer – Multimodal Therapy
MEDIASTINUM
39 Mediastinal Anatomy and Mediastinoscopy
40 Anterior Mediastinal Masses
41 Middle Mediastinum
42 The Posterior Mediastinum
43 Surgical Treatment of Hyperhidrosis
THE FUTURE
44 The Use of Genetic Science in Thoracic Disease
45 Innovative Therapy and Technology


SECTION II ***** Cardiac

BASIC SCIENCE
46 ***** Cardiac Anatomy
47 Atherosclerosis, Restenosis and Vascular Biology
48 Physiology of the Coronary Circulation
49 Physiology of the Myocardium
50 Ventricular Mechanics
51 Shock and Sepsis
52 Tissue Regeneration
53 Blood Coagulation, Transfusion, and Conservation
DIAGNOSTIC PROCEDURES
54 Coronary Angiography, Valve and Hemodynamic Assessment
55 CT Applications in Cardiovascular Disease
56 Cardiovascular Magnetic Resonance Imaging in Cardiovascular Diagnosis
57 Nuclear Cardiology and PET in the Assessment of Patients with Cardivascular Disease
58 Diagnostic Echocardiography
MEDICAL AND CATHETER-BASED TREATMENT OF CARDIAC DISASE
59 Interventional Cardiology
60 Medical Management of Acute Coronary Syndromes
61 Non Antherosclorotic Vascular Disease
62 Pharmacologic Management of Heart Failure
63 The Coronary Circulation: Dietary and Pharmacologic Management of Atherosclerosis
PERIOPERATIVE AND INTRAOPERATIVE CARE OF THE CARDIAC SURGICAL PATIENT
64 ***** Cardiac Anesthesia
65 Critical Care for the ***** Cardiac Patient
66 Cardiopulmonary Bypass---Technique and Pathophysiology
67 Myocardial Protection
68 Clinical Quality and Cardiac Surgery
SURGICAL MANAGEMENT OF AORTIC DISEASE
69 Surgery of the Aortic Root and Ascending Aorta
70a Surgery of the Aortic Arch
70b Descending Thoracic and Thoracoabdominal Aortic Surgery
70c Acute Aortic Dissection
70d Chronic Aortic Dissection
71 Endovascular Therapy for the Treatment of Thoracic Aortic Aneurysms and Dissections
72 Occlusive Disease of Branches of the Aorta and Peripheral Angiography Intervention


I Occlusive Disease of the Supraaortic Trunk and Management of Simultaneous Surgical Carotid/Coronary Disease



II Peripheral Angiography and Percutaneous Intervention

SURGICAL MANAGEMENT OF VALVULAR HEART DISEASE
73 Valve Replacement Therapy Options, History and Valve Types
74 Acquired Aortic Valve Disease
75 Acquired Disease of Mitral Valve
76 Acquired Disease of the Tricuspid Valve
77 Prosthetic Valve Endocarditis
78 Thrombosis and Thromboembolism of Prosthetic Cardiac Valves and Extracardiac Prostheses
79 Robotic and Novel Visualization Systems
MANAGEMENT OF CARDIAC ARRHYTHMIAS
80 Cardiac Devices for the Treatment of Bradyarrhythmias and Tachyarrhythmias
81 Catheter Ablation of Arrhythmias
82 Surgical Treatment of Cardiac Arrhythmias
SURGICAL TREATMENT OF CORONARY ARTER DISEASE AND ITS COMPLICATIONS
83 Coronary Artery Bypass Grafting
84 Alternative Approaches to Surgical Coronary Artery Bypass Grafting
85 Bypass Conduit Options
86 Redo Coronary Artery Bypass Graft (CABG)
87 Ischemic MR and Rupture of Papillary Muscles
88 Postinfarction Ventricular Septal Defect
89 Therapeutic Angiogenesis
90 Transmyocardial Laser Revascularization
SURGICAL MANAGEMENT OF HEART FAILURE
91 Pericardium and Constrictive Pericarditis
92 Surgical Management of Hypertrophic Cardiomyopathy
93 Left Ventricular Assist Devices
94 Total Artificial Heart
95 Heart Transplantation
96 Heart-Lung Transplantation
97 Left Ventricular Reconstruction and the Surgical Treatment of the Failing Heart
98 Cell Transplantation for Cardiovascular Disease
99 Surgery for Pulmonary Embolization
100 Tumors of the Heart


SECTION III Congenital Heart Surgery

101 Embryology and Molecular Genetics
102 Segmental Anatomy
103 Diagnostic Imaging: Echocardiography and Magnetic Resonance Imaging
104 Cardiac Catheterization and Catheter-Based Interventions
105a Surgical Approaches and Cardiopulmonary Bypass
105b Mechanical Circulatory Support in Children
106 Pediatric Anesthesia and Critical Care
107 Congenital Tracheal Diseases
108 Patent Ductus Arteriosus and Vascular Rings
109 Coarcation, Aortopulmonary Collaterals and Arterio-pulmonary Shunts
110 Atrial Septal Defect and Cor Triatriatum
111 Surgical considerations in pulmonary vein anomalies
112a Atrioventricular Canal Defects: Partial (Ostium Primum and Transitional)
112b Atrioventricular Canal Defects: Complete Canal Defects
113 Ventricular Septal Defect and Double-Outlet Right Ventricle
114 Pulmonary Atresia With Intact Ventricular Septum
115 Tetralogy of Fallot with Pulmonary Stenosis
116 Tetralogy of Fallot with Pulmonary Atresia
117 Right Ventricle to Pulmonary Artery Conduits
118 Truncus Arteriosus and Aortopulmonary Window
119 Interrupted Aortic Arch
120 Surgery for Congenital Anomalies of the Aortic Valve and Root
121 Surgery for Congenital Anomalies of the Coronary Arteries
122 Transposition of the Great Arteries
123 Transposition of the Great Arteries Complex
124 Anatomically Corrected Transposition
125 Congenital Anomalies of the Mitral Valvenbr
126 Obstruction of the Left Ventricular Outflow and Shone?s Syndrome
127 Hypoplastic Left Heart Syndrome
128 Management of Single Ventricle and Cavopulmonary Connections
129 Ebstein?s Anomaly
130 ***** Congenital Cardiac Surgery
131 Surgery for Arrhythmias and Pacemakers in Children


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High-yield embryology By Ronald W. Dudek free book download

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High-Yield Embryology

Product Details
»Book Publisher: Lippincott Williams & Wilkins (01 January, 2001)
»ISBN: 0781721326
»Book author: Ronald W Dudek

Book Description:

The High-Yield(TM) Series extracts the most important information on each topic and presents it in a concise, uncluttered fashion to prepare students for the USMLE. New to High-Yield(TM) Embryology, Second Edition are 26 chapters that cover topics from prefertilization events and the embryonic period, to cardiovascular, digestive, urinary, reproductive, respiratory, head and neck, nervous, eye, ear, skeletal, and muscular system development. Also included are chapters on chromosomal abnormalities, inherited diseases, teratology and more. Radiographs, magnetic resonance (MR) images, and photos of congenital malformations are included, with pathology related to embryological development and clinical findings.

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Molecular Embryology: Methods and Protocols by Paul T. Sharpe (Editor), Ivor Mason (Editor) free book download


Molecular Embryology: Methods and Protocols
by Paul T. Sharpe (Editor), Ivor Mason (Editor)

Product Details
* Hardcover: 756 pages
* Publisher: Humana Press; 1st edition (January 15, 1999)
* Language: English
* ISBN-10: 0896033872
* ISBN-13: 978-0896033870

Table of Contents

Part I. Mouse Embryo

The Mouse as a Developmental Model
Paul T. Sharpe

Culture of Postimplantation Mouse Embryos
Paul Martin and David L. Cockroft

Organ Culture in the Analysis of Tissue Interactions
Irma Thesleff and Carin Sahlberg

Treatment of Mice with Retinoids In Vivo and In Vitro: Skeletal Staining
Gillian M. Morriss-Kay

Cell Grafting and Labeling in Postimplantation Mouse Embryos
Gabriel A. Quinlan, Paul A. Trainor, and Patrick P. L. Tam

Production of Transgenic Rodents by the Microinjection of Cloned DNA Into Fertilized One-Celled Eggs
San Ling Si-Hoe and David Murphy

Cre Recombinase Mediated Alterations of the Mouse Genome Using Embryonic Stem Cells
Anna-Katerina Hadjantonakis, Melinda Pirity, and András Nagy

Gene Trapping in Mouse Embryonic Stem Cells
Jane Brennan and William C. Skarnes

Production and Growth of Conditionally Immortal Cell Lines from the H-2KbtsA58 Transgenic Mouse
Mark Noble

Reporter Genes for the Study of Transcriptional Regulation in Transgenic Mouse Embryos
Jonathan D. Gilthorpe and Peter W. J. Rigby

Application of lacZ Transgenic Mice to Cell Lineage Studies
Paul A. Trainor, Sheila X. Zhou, Maala Parameswaran, Gabriel A. Quinlan, Monica Gordon, Karin Sturm, and Patrick P. L. Tam

Mouse Primordial Germ Cells: Isolation and In Vitro Culture
Patricia A. Labosky and Brigid L. M. Hogan

Part II. Chicken Embryo

The Avian Embryo: An Overview
Ivor Mason

Chick Embryos: Incubation and Isolation
Ivor Mason

New Culture
Amata Hornbruch

Grafting Hensen's Node
Claudio D. Stern

Grafting of Somites
Claudio D. Stern

Manipulating the Chick Embryo: Notochord Grafts
Andrew Lumsden and Susanne Dietrich

Transplantation of Avian Neural Tissue
Sarah Guthrie

Grafting of Apical Ridge and Polarizing Region
Cheryl Tickle

Tissue Recombinations in Collagen Gels
Marysia Placzek and Kim Dale

Quail–Chick Chimeras
Marie-Aimée Teillet, Catherine Ziller, and Nicole M. Le Douarin

Using Fluorescent Dyes for Fate Mapping, Lineage Analysis, and Axon Tracing in the Chick Embryo
Jonathan D. W. Clarke

Part III. Amphibian Embryos

An Overview of Xenopus Development
C. Michael Jones and Jim Smith

Mesoderm Induction Assays
C. Michael Jones and Jim Smith

Experimental Embryological Methods for Analysis of Neural Induction in the Amphibian
Ray Keller, Ann Poznanski, and Tamira Elul

A Method for Generating Transgenic Frog Embryos
Enrique Amaya and Kristen L. Kroll

Axolotl/newt
Malcolm Maden

Part IV. Zebrafish

The Zebrafish: An Overview of Its Early Development
Nigel Holder and Qiling Xu

Small-Scale Marker-Based Screening For Mutations in Zebrafish Development
Peter D. Currie, Thomas F. Schilling, and Philip W. Ingham

Transgenic Zebrafish
Trevor Jowett

Microinjection of DNA, RNA, and Protein into the Fertilized Zebrafish Egg For Analysis of Gene Function
Nigel Holder and Qiling Xu

Retinoids in Nonmammalian Embryos
Malcolm Maden

Part V. Nonvertebrate Chordates

Protochordates
Peter W. H. Holland and Hiroshi Wada

Part VI. Retrovirus

Gene Transfer to the Rodent Embryo by Retroviral Vectors
Grace K. Pavlath and Marla B. Luskin

Gene Transfer in Avian Embryos Using Replication-Competent Retroviruses
Cairine Logan and Philippa Francis-West

Part VII. Molecular Techniques

Subtractive Hybridization and Construction of cDNA Libraries
Bruce Blumberg and Juan Carlos Izpisúa Belmonte

Differential Display of Eukaryotic mRNA
Antonio Tugores and Juan Carlos Izpísua Belmonte

RT-PCR on Embryos Using Degenerate Oligonucleotide Primers
Anthony Graham

Single-Cell RT-PCR cDNA Subtraction
Damian L. Weaver, César Núñez, Clare Brunet, Victoria Bostock, and Gerard Brady

In Situ Hybridization of Radioactive Riboprobes to RNA in Tissue Sections

Radma Mahmood and Ivor Mason. In Situ Hybridization to RNA in Whole Embryos
Huma Shamim, Radma Mahmood, and Ivor Mason

Wholemount In Situ Hybridization to Xenopus Embryos
C. Michael Jones and James C. Smith

Wholemount In Situ Hybridization to Amphioxus Embryo
Peter W. H. Holland

In Situ Hybridization to Sections (Nonradioactive)
Maria Rex and Paul J. Scotting

Immunohistochemistry Using Polyester Wax
Andrew Kent

Immunohistochemistry on Whole Embryos
Ivor Mason

Whole Embryo Assays for Programmed Cell Death
Anthony Graham

Gene Interference Using Antisense Oligodeoxynucleotides on Whole Chick Embryos: Optimal Ring and Roller-Bottle Culture Technique
Jonathan Cooke and Alison Isaac

Protein Techniques: Immunoprecipitation, In Vitro Kinase Assays, and Western Blotting
David I. Jackson and Clive Dickson

Part VIII. Microscopy and Photography

Microscopy and Photomicrography Techniques
Richard J. T. Wingate

Index

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Regulation of Sertoli Cell and Germ Cell Differentiation By Ralph Brehm, Inc NetLibrary, Klaus Steger free book download

Regulation of Sertoli Cell and Germ Cell Differentiation (Advances in Anatomy, Embryology and Cell Biology)

Product Details
»Book Publisher: Springer (26 October, 2005)
»ISBN: 3540257500
»Book author: R. Brehm, K. Steger

Book Description:
Unwanted childlessness affects approximately one in six couples worldwide. Although the exact proportion of the predominant cause of the problem remains controversial, according to the World Health Organization, in nearly 40 % of cases the cause can be attributed to the female, in 20 % to the male, in 25 % to both, and in 15 % the cause remains unknown. Based on these figures, the incidence of male factor infertility in the general population is approximately 7 %. The majority of these men, approximately 30 %, experience irreversible idiopathic infertility and cannot father children without some form of medical intervention. Male factor infertility, in addition, may be caused by testicular germ cell cancer which is known to represent the most common cancer among young men, aged 15 to 35 years, in Western industrialized countries. The number of affected men has increased dramatically over the past 50 years. There is now growing evidence that human testicular germ cell cancer originates from fetal germ cells exhibiting an aberrant programme of gene expression and tumour progression may be favoured by an aberrant Sertoli cell germ cell communication. The intention of the present monograph is to shed more light on the regulation of Sertoli cell and germ cell differentiation. Involving knockout and transgenic mouse models, the authors focus on male factor infertility that might be related to altered maturation of Sertoli cells, male factor infertility that might be due to incorrect histone-to-protamine exchange in haploid spermatids, and progression of testicular germ cell cancer that might be favoured by an aberrant Sertoli cell germ cell communication.

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Langman's essential medical embryology By Thomas W.. Sadler, Jan Langman, Phillip M. Ecker free book download

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Product Details
Book Publisher: Lippincott Williams & Wilkins (26 March, 2003)
ISBN: 0781743109
Book author: Thomas Sadler
Amazon Rating: 4.0

Book Description:
First published in 1963, this comprehensive text on embryology has long been respected for its scientific authority, pedagogy, and clinical relevance to medical education. Known for its outstanding illustrations and clear and concise writing, the text covers almost all aspects of embryology that would be of interest to medical students and their instructors. The Ninth Edition follows the organization of previous editions, first structured by chronology and then by system. New to this edition are 30 additional illustrations and clinical images, as well as a chapter on prenatal diagnosis and birth defects. Also included is Simbryo, an electronic supplement consisting of Flash animation showing the evolution of early embryonic development and different organ systems, as well as birth defects.

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Stem Cell Biology (Cold Spring Harbor Monograph Series, 40) free book download

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Product Details
Book Publisher: Cold Spring Harbor Laboratory Press (01 February, 2001)
ISBN: 0879695757
Book author: Daniel R. Marshak, Richard L. Gardner, David Gottlieb

Book Description:
Stem cells are the focus of intense interest from a growing, multidisciplinary community of investigators with new tools for isolating and characterizing these elusive cell types. This volume, which features contributions from many of the world’s leading laboratories, provides a uniquely broad and authoritative basis for understanding the biology of stem cells and the current excitement about their potential for clinical exploitation. It is an essential work of reference for investigators in embryology, hematology, and neurobiology, and their collaborators in the emerging field of regenerative medicine.

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Handbook of Pediatric Strabismus and Amblyopia free book download



Publisher: Springer
Number Of Pages: 559
Publication Date: 2006-04-19
Sales Rank: 897152
ISBN / ASIN: 0387279245
EAN: 9780387279244
Binding: Paperback
Manufacturer: Springer
Studio: Springer
Average Rating:
Total Reviews:

Book Description: )
Based on Dr. Wright’s classic major reference, Handbook of Pediatric Strabismus and Amblyopia outlines the latest findings in diagnosing the most commonly presenting problems in pediatic cases, offering the most complete assessment tools for accurate diagnosis and then best treatment options. Distilling the essentials of these prevelant and sometimes complicated cases into a portable, complete and authorative pocket reference, this handbook offers a complete picture of how to best treat pediatric patients. Specifically, the introductory chapters on the specifics of pediatric ophthalmology (embryology, post-natal development and the pediatric exam) will help newcomers to pediatric practice fully grasp the subtle differences in pediatric care. The chapters are written by leading experts in the field and are presented in a user-friendly format, relying on heavily illustrated in color plates, clincally helpful tables, charts, and decision-making guidelines. This approach will enable the practitioner (whether specialist or generalist) to make the most accurate diagnosis and choose the most effective treatment

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Improving Birth Outcomes: Meeting the Challenge in the Developing World free book download


Description
Birth outcomes have improved dramatically worldwide in the past 40 years. Yet there is still a large gap between the outcomes in developing and developed countries. This book addresses the steps needed to reduce that gap. It reviews the available statistics of low birth weight, prematurity, and birth defects; reviews current knowledge and practices of a healthy pregnancy, identifies cost-effective opportunities for improving birth outcomes and supporting families with an infant handicapped by birth problems, and recommens priority research, capacity building, and institutional and global efforts to reduce adverse birth outcomes in developing countries. The committee has based its study on data and information from several developing countries, and provides recommendations that can assist the March of Dimes, Centers for Disease Control and Prevention, and NIH in tailoring their international program and forging new partnerships to reduce the mortality and morbidity associated with adverse birth outcomes.
Table of Contents

Executive Summary 3
1 Introduction 17
2 Reducing Maternal Mortality and Morbidity 43
Causes of Maternal Morbidity and Mortality 44
Infections 48
Interventions 52
3 Reducing Neonatal Mortality and Morbidity 91
Causes of Neonatal Morbidity and Mortality 91
Interventions 102
4 Reducing Fetal Mortality 135
Factors Contributing to Late Fetal Deaths 138
Interventions 148
5 Improving Birth Outcomes within Health Care Systems 165
The Evidence Base 166
Primary Care and Referral 166
Building Capacity for Reproductive Health Care 178
Managing Health Care Systems 184
6 The Problem of Low Birth Weight 205
Patterns of Occurrence 205
Causes of IUGR and Preterm Birth 207
Consequences of IUGR and Preterm Birth 212
Interventions to Prevent Preterm Birth and IUGR 217
7 Reducing Mortality and Morbidity from Birth Defects 237
Patterns of Occurrence 238
Causes of Birth Defects 238
Reducing the Impact of Birth Defects 248
8 Preventing Perinatal Transmission of HIV 263
The HIV/AIDS Epidemic 263
Interventions to Prevent HIV Transmission 267
9 Summing Up: The Way Forward 293
App. A: Workshop Agenda 301
App. B: Defining Developing Countries 305
App. C The Essential Competencies of a Skilled Birth Attendant 310
App. D: Committee Biographies 314
App. E: Dissenting Note 320
Glossary 324
Acronyms 334
Index 337

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Applied Statistical Designs for the Researcher (Biostatistics) free book download


Product Details
Book Publisher: CRC
ISBN: 0824740858
Book author: Daryl S. Paulson

Book Description:
Showcasing a discussion of the experimental process and a review of basic statistics, this volume provides methodologies to identify general data distribution, skewness, and outliers. It features a unique classification of the nonparametric analogs of their parametric counterparts according to the strength of the collected data. Applied Statistical Designs for the Researcher discusses three varieties of the Student t test, including a comparison of two different groups with different variances; two groups with the same variance; and a matched, paired group. It introduces the analysis of variance and Latin Square designs and presents screening approaches to comparing two factors and their interactions.

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Goldfrank’s Toxicologic Emergencies free book download



By Neal E. Flomenbaum, Lewis R. Goldfrank, Robert S. Hoffman, Mary Ann Howland, Neal A. Lewin, Lewis S. Nelson,

Publisher: McGraw-Hill Professional
Number Of Pages: 1981
Publication Date: 2006-03-28
Sales Rank: 186988
ISBN / ASIN: 0071437630
EAN: 9780071437639
Binding: Hardcover

Book Description:
The #1 reference in the field for the last quarter of a century, Goldfrank's Toxicologic Emergencies, Eighth Edition, has been completely updated to equip emergency physicians with today's most authoritative guide to clinical toxicology. The book presents unsurpassed coverage of all aspects of toxicologic emergencies_from pharmacology and clinical presentation…to treatment guidelines and case studies. Using a unique case-study approach, Goldfrank's fully examines general principles and techniques…the biochemical and molecular basis of toxicology…and how toxins affect vital signs, organs, and systems throughout the body. The Eighth Edition now features:

A case-based approach that maximizes understanding of clinical applications of the material.
Antidotes in depth, offering easy-to-find, detailed guidance on the use of antidotes.
Quick-reference tables on inside covers, providing immediate access to “must-have” vital-sign statistics, lab values, and common equations.
New to the Eighth Edition: expanded coverage of bioterrorism, inhalant abuse, and international considerations
A companion website with more than 1200 self- assessment questions and annotated answers critical cases in medical toxicology reviewed in detail, 100 color photos of plants, mushrooms, spiders, snakes, marine life, and dermatologic reactions of toxicologic importance

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Colorectal Cancer free book download



Publisher: Wiley
Number Of Pages: 200
Publication Date: 2005-11-29
Sales Rank: 2574087
ISBN / ASIN: 1861563345

Book Description:
Nurses should have the most up-to-date knowledge to provide accurate information and competent nursing care to patients with colorectal cancer. Swan addresses those issues in a very thorough and comprehensive manner.
Chapters on the role of the colorectal nurse specialist, epidemiology and genetics, diagnosis, investigations and different treatments make this book essential reading for any colorectal nurse specialist.
Colorectal cancer is the third most common cancer in men, and the second most common cancer in women in the UK. Colorectal Cancer is a very important book in this field. As mortality statistics continue to rise, this book addresses the issues surrounding colorectal cancer. It is vital to care for and attend to the needs of these patients.
Download Description:
Nurses should have the most up-to-date knowledge to provide accurate information and competent nursing care to patients with colorectal cancer. Swan addresses those issues in a very thorough and comprehensive manner. Chapters on the role of the colorectal nurse specialist, epidemiology and genetics, diagnosis, investigations and different treatments make this book essential reading for any colorectal nurse specialist. Colorectal cancer is the third most common cancer in men, and the second most common cancer in women in the UK. Colorectal Cancer is a very important book in this field. As mortality statistics continue to rise, this book addresses the issues surrounding colorectal cancer. It is vital to care for and attend to the needs of these patients.

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